10%聚己二酸乙二醇酯/401有机担体 工业乙酸异丙酯的测定填充柱

将醋酸、异丙醇和浓硫酸加入搪瓷釜，搅拌下加热回流10h以上，降温后用碳酸氢钠或碳酸钠饱和溶液中和pH值7～8，用饱和食盐水溶液洗涤，再用水洗涤，静置分去水层后，用无水硫酸钠或硫酸镁进行干燥，过滤后加入精馏塔进行精馏，收集85～95℃的馏分，即为成品。

精制方法：常含有水、乙酸和异丙醇等杂质。精制时于100mL酯中加入50g碳酸钾，充分摇动以除去酸。再用浓的氯化钙溶液洗涤除去醇，无水氯化钙干燥1昼夜后蒸馏。

1.主要用作涂料、印刷油墨等的溶剂，也是工业上常用的脱水剂，药物生产中的萃取剂及香料组分；

2.主要用作药物的提取溶剂、涂料溶剂、印刷油墨溶剂、化学反应溶剂等。该品呈水果香气，稀释后有苹果香气，天然品存在于菠萝、梨、可可等中，是中国GB2760-86规定为允许使用的食用香料。主要用以配制朗姆酒香精和水果型香料的溶剂。


浩瀚色谱（山东）应用技术开发有限公司，采用填充柱10%聚己二酸乙二醇酯/401有机担体测定工业乙酸异丙酯中杂质：水分，异丙醇，乙酸异丙酯，柱效高，分离好，峰型对称，结果满意。


工业乙酸异丙酯的测定填充柱  测试谱图：




Packed column for the determination of industrial isopropyl acetate
Packed column for the determination of industrial isopropyl acetate Details:

Name: Packed Column
Fixative: 10% polyethylene adipate

Carrier: 401 organic carrier (0.25mm-0.18mm)/60-80 mesh

Ratio: Carrier: Fixative = 100:10
Model: 10%PEA/401


Isopropyl acetate; 2-propyl acetate
Colorless transparent liquid with fruity fragrance. Volatile, miscible with most organic solvents such as alcohols, ketones and ethers. 2.9% by weight in water at 20°C.

chemical properties
It is flammable, its vapor and air can form explosive mixture. In case of open fire and high heat, it will cause combustion and explosion; it can react strongly with oxidants. Its vapor is heavier than air, and it can spread to a considerable distance at a lower place, and it will cause flashback in case of an open flame. Combustion (decomposition) products: carbon monoxide, carbon dioxide, and water.

Add acetic acid, isopropanol and concentrated sulfuric acid to the enamel kettle, heat to reflux for more than 10 hours with stirring, neutralize with sodium bicarbonate or saturated sodium carbonate solution to pH 7-8 after cooling, wash with saturated saline solution, then wash with water, and let After the water layer is removed, dried with anhydrous sodium sulfate or magnesium sulfate, filtered, and then added to a rectifying tower for rectification, and the fractions at 85 to 95°C are collected, which is the finished product.
Refining method: often contains impurities such as water, acetic acid and isopropanol. During purification, 50 g of potassium carbonate was added to 100 mL of ester and shaken well to remove the acid. Then wash with concentrated calcium chloride solution to remove alcohol, dry with anhydrous calcium chloride for 1 day and night, and then distill.


1. It is mainly used as a solvent for coatings, printing inks, etc., and is also a commonly used dehydrating agent in industry, an extractant and a fragrance component in pharmaceutical production;
2. Mainly used as extraction solvent of medicine, coating solvent, printing ink solvent, chemical reaction solvent, etc. The product has a fruity aroma, and has an apple aroma after dilution. The natural product exists in pineapple, pear, cocoa, etc. It is a permitted edible spice specified by China GB2760-86. It is mainly used to prepare the solvent of rum flavor and fruit flavor.


Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. uses packed column 10% polyethylene adipate/401 organic support to determine impurities in industrial isopropyl acetate: moisture, isopropyl alcohol, isopropyl acetate, column efficiency High, the separation is good, the peak shape is symmetrical, and the results are satisfactory.


Determination of Industrial Isopropyl Acetate Packed Column Test Spectrum: