OV-624毛细管柱 《中国药典》中GC法测定甲醇量

固定液：6%氰丙基苯基-94%甲基聚硅氧烷

极性： 中等极性

使用温度：40℃～240℃

规格：30m*0.53mm*3um

型号：OV-624

应用：《中国药典》中GC法测定甲醇量

      滕州市浩瀚色谱仪器技术服务有限公司，讨论《中国药典》2010年版第三增补本中GC法测定甲醇量检查法中存在的问题。方法分别比较《中国药典》2010年版一部附录ⅨT及第三增补本所载方法进行实验,并对结果进行分析比较。结果《中国药典》2010年版第三增补本所载甲醇量测定方法在实际操作中存在顶空进样平衡时间及分流比设定不合理的问题。结论应延长平衡时间,增大分流比比例,以更好运用于实际检验工作。




Determination of methanol content by GC method in "Chinese Pharmacopoeia"
The GC method in "Chinese Pharmacopoeia" to determine the amount of methanol Details:

Name: Capillary Column
Fixing fluid: 6% cyanopropyl phenyl-94% methyl polysiloxane

Polarity: medium polarity

Operating temperature: 40℃～240℃

Specification: 30m*0.53mm*3um

Model: OV-624

Application: GC method in "Chinese Pharmacopoeia" to determine the amount of methanol

       Tengzhou Haohan Chromatography Instrument Technology Service Co., Ltd. discussed the problems in the GC method for the determination of methanol content in the third supplement to the 2010 edition of the Chinese Pharmacopoeia. Methods Compare the methods contained in Appendix ⅨT and Third Supplement of the 2010 edition of Chinese Pharmacopoeia to conduct experiments, and analyze and compare the results. Results The method for measuring the amount of methanol contained in the third supplement to the 2010 edition of the Chinese Pharmacopoeia had problems in the actual operation of unreasonable headspace sampling equilibrium time and split ratio settings. Conclusion The balance time should be prolonged and the ratio of shunt ratio should be increased to better use it in actual inspection work.